[ Anastasia finds it in her best interest to keep the number she trusts to very few people, which is perhaps why she feels uncomfortable with Skye being the one in charge of something so important. But Skye was the only one with the skill set they needed for that. ]

The people who purport to not keep any secrets are the ones I find usually have the most to hide. I'm trusting you with this, so if I see good results then if there needs to be a next time I'll certainly know to trust you better. For now I'm just relying on Loki's judgment. It's nothing personal.

[ And even then, Loki she has trouble trusting and she likes him. ]